SAG 21k
Animals onlyNot measured in peopleResearch onlySmall moleculeAlso Hedgehog agonist 1
A stronger version of the laboratory chemical that switches the Hedgehog signal on, sold under several names.
A second-generation SAG analogue and small-molecule Smoothened agonist, more potent than SAG, with activity in animals when given systemically. Also sold as Hedgehog agonist 1, or compound 21k: one molecule, CAS 946002-48-8.
Risks. Put in one spot in a mouse it stayed there, which matters because switching this pathway on throughout the body is what drives certain cancers.
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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.
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