SAG
Cells and tissue onlyNot measured in peopleResearch onlySmall molecule
A laboratory chemical that switches on the Hedgehog signal inside a cell.
A small-molecule Smoothened agonist, acting downstream of PTCH1 to activate canonical Hedgehog signalling. A laboratory compound.
Risks. Leaving this pathway switched on is what causes a common skin cancer, and there is no safety information for this compound in people.
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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.
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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.