rhBMP-7

Inside the plate · In BMP and TGF-β

3D structure of BMP-7 (OP-1) (PDB 1BMP)
Structure: BMP-7 (OP-1). Image from the RCSB PDB (RCSB.org) of PDB ID 1BMP (Griffith et al., 1996)

Withdrawn or never marketedMeasured in people, not heightPlaced at surgeryProtein or enzymeAlso OP-1

A bone-building protein allowed only for fractures that would not heal and repeat spine surgery.

The other recombinant BMP taken to clinic, cleared in the US only under a humanitarian exemption for stubborn long-bone non-unions and revision lumbar fusion.

Risks. Its package insert ruled it out for anyone under 18 or still growing, and in pregnancy, and over a third of patients made antibodies to it.

On this page

  • At the growth plate, members only
  • Risks and side effects, members only

The rest of this page is for members

What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.

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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.