Rapamycin
Approved, for something elseHeight measured in peopleBy mouthSmall moleculeAlso sirolimus
A transplant drug that blocks mTOR. It is the standard way of switching on the cell’s clean-up system.
An approved immunosuppressant that inhibits mTORC1 directly, used to prevent transplant rejection. It is also the reference autophagy inducer, which is why it appears in this pathway at all.
Risks. Its label carries the strongest class of warning, for serious infections and cancers from suppressing the immune system. For this site there is one more harm: children on it have grown more slowly.
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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.
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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.