Pterosin B
Animals onlyNot measured in peopleResearch onlySmall molecule
A compound from bracken fern that blocks one kinase in the chain that controls when cartilage cells swell.
A natural compound from bracken fern, identified in a screen as an inhibitor of the kinase SIK3 and developed as an osteoarthritis candidate. It is also the hydrolysis product of ptaquiloside, bracken’s principal carcinogen.
Risks. Untested in people, and it comes from a plant classified as possibly cancer-causing.
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