Ponatinib

Inside the plate · In FGF and FGFR3

Chemical structure of Ponatinib
Structure: Ponatinib, PubChem CID 24826799

Approved, for something elseMeasured in people, not heightBy mouthSmall molecule

A leukaemia drug that blocks the receptor slowing cartilage growth, among many other targets.

A leukaemia drug, and a type II kinase inhibitor: it binds FGFR3 in its inactive, DFG-out conformation. It hits this receptor among many others. Oncology only.

Risks. Its label carries the strongest class of warning, for blocked arteries, blood clots, heart failure and liver damage.

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  • Risks and side effects, members only

The rest of this page is for members

What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.

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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.