Pegozafermin

Hormones · In JAK2, STAT5B and GH resistance

In human trialsMeasured in people, not heightBy injectionProtein or enzyme

A copy of the fasting hormone FGF21, in late trials for liver disease in adults.

An FGF21 analogue, in phase 3 for non-cirrhotic MASH and for compensated cirrhosis due to MASH, both in adults aged 18 to 80. Not approved.

ClinicalTrials.govClinicalTrials.gov

Risks. In the adult trials its common side effects were nausea and diarrhoea. It has only been given to adults.

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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.

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