GrowTallest

PD98059 / U0126

Inside the plate · In FGF and FGFR3

Chemical structure of 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
Structure: 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one, one of the pair, PubChem CID 4713

Animals onlyNot measured in peopleResearch onlySmall molecule

Two laboratory chemicals that block MEK, a step in the message from the receptor that slows cartilage growth; neither is a medicine.

MEK1/2 inhibitors, and research reagents rather than drugs. They act allosterically, preventing ERK1/2 phosphorylation. Not orally available, and used in vitro and in animals only.

Risks. No safety information: these are laboratory chemicals, not something anyone takes.

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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.

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