PAPP-A2 protein
Animals onlyNot measured in peopleResearch onlyProtein or enzymeAlso rhPAPP-A2
The missing enzyme given as a drug so it can cut IGF-1 loose from its carriers, and it has never been given to a person.
The missing protease supplied directly as a protein, so that the carrier proteins holding IGF-1 get cut. Not approved and not in trials, with no human data of any kind.
Risks. It has never been given to a person, so nothing at all is known about its safety.
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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.
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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.