IGF bioavailability
Why the IGF-1 figure on a blood test is not the signal a growth plate receives, and the protease and inhibitor pair that decides how much of it gets loose.
Circulating IGF-1 is nearly all bound (see IGF-1 and IGF-1R). Release from the carriers is a separate variable from how much the liver makes, and it has its own machinery.
In this article
- How IGF-1 is let loose
- What the human genetics shows
- Compounds
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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.