NMN and nicotinamide riboside

Inside the cell · In Sirtuins and autophagy

Chemical structure of Nicotinamide mononucleotide (NMN)
Structure: Nicotinamide mononucleotide (NMN), one of the pair, PubChem CID 14180

Food or supplementMeasured in people, not heightBy mouthNutrient

Two supplements that top up NAD⁺, the fuel the sirtuin enzymes burn.

Two precursors that feed the NAD⁺ salvage pathway, sold as supplements. Nicotinamide riboside is converted to NMN first, and both end as NAD⁺, the molecule sirtuins consume every time they work.

Risks. Tolerated in short adult trials, and that is all that is known. No safety data in children, none long-term, and some trials were funded by the companies selling them.

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