Mocetinostat

In human trialsMeasured in people, not heightBy mouthSmall molecule
An experimental cancer drug that blocks a set of enzymes controlling which genes a cell reads.
An orally available benzamide that inhibits HDAC1, 2, 3 and 11 — class I plus the class IV enzyme. Developed for cancer throughout, through more than twenty registered trials, and never approved anywhere. Its sponsor de-prioritised it, and two trials record termination for that reason rather than for safety.
Risks. Common fatigue and gut upset, with fluid around the heart in about one patient in ten.
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