METTL3 complex activators

Inside the cell · In METTL3 and m6A

Cells and tissue onlyNot measured in peopleResearch onlySmall moleculeAlso Selberg series

Laboratory compounds that make the enzyme writing the RNA mark work faster.

A small series of compounds found by in silico screening, confirmed to bind the METTL3 writer complex and to raise its enzymatic activity rather than block it. Research compounds.

Cell Rep, 2019

Risks. They made HIV multiply faster in infected cells.

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