Lithium

Inside the cell · In GSK3

Photo: rods of lithium metal sealed in a glass ampoule
Image: Hi-Res Images of Chemical Elements, CC BY 3.0, via Wikimedia Commons

Approved, for something elseMeasured in people, not heightBy mouthSmall molecule

A long-established medicine that happens to block GSK3, and is watched closely in the people who take it because its safe range is narrow.

Inhibits GSK3 directly by competing with magnesium, and indirectly through inositol depletion. The one compound in this class with decades of human use, prescribed and monitored on a narrow therapeutic index for reasons unrelated to bone.

Risks. It carries the strongest class of warning because the poisonous dose sits close to the working one, so anyone taking it needs regular blood tests.

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  • Risks and side effects, members only

The rest of this page is for members

What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.

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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.