Glycyrrhizin

Hormones · In Inflammation and growth failure

Chemical structure of Glycyrrhizin
Structure: Glycyrrhizin, PubChem CID 14982

Food or supplementMeasured in people, not heightBy mouthNutrient

The sweet compound in liquorice root, used as a flavouring. In research it blocks an alarm signal released by damaged cells.

The sweet triterpene saponin of liquorice root, many times sweeter than sugar and used as a flavouring and a supplement. In cartilage research it is used as an inhibitor of HMGB1, an alarm protein released by damaged cells, rather than as a direct blocker of the inflammatory relay.

Risks. It raises blood pressure and drains potassium, measurably and even at ordinary amounts, by stopping the kidney switching off cortisol. Severe cases cause muscle damage and heart rhythm problems.

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