Entinostat
Approved, for something elseMeasured in people, not heightBy mouthSmall moleculeAlso MS-275
A breast cancer drug approved in China that blocks only some of the HDAC enzymes.
A class I selective HDAC inhibitor. Approved in China in 2024, with an aromatase inhibitor, for HR-positive HER2-negative advanced breast cancer. Not approved in the US or Europe.
Risks. No US or European regulator has set out its risks. In its main trial two patients in three had a severe side effect, most often a sharp fall in infection-fighting white cells.
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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.
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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.