Canakinumab
Approved, for something elseHeight measured in peopleBy injectionAntibodyAlso Ilaris
An injected antibody that mops up one inflammation signal, licensed for several rare inflammatory diseases in children and adults.
Human monoclonal antibody against IL-1β, given subcutaneously. Approved for active Still's disease including systemic JIA and adult-onset Still's disease in patients 2 years of age and older, for cryopyrin-associated periodic syndromes from 4 years, for TRAPS, HIDS/mevalonate kinase deficiency and familial Mediterranean fever, and for gout flares in adults.
Risks. No boxed warning, but its label warns of serious and unusual infections, a suppressed immune system whose effect on cancer risk is unknown, and severe allergic reactions.
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