Alprostadil
Approved, for something elseMeasured in people, not heightBy injectionSmall moleculeAlso Prostin VR Pediatric
PGE1 itself, dripped into a vein to hold a heart vessel open in a newborn whose heart defect needs that vessel, until surgery.
Prostaglandin E1 itself, given by continuous intravenous infusion into a large vein or through an umbilical artery catheter. Approved as palliative rather than definitive therapy, to hold the ductus arteriosus patent until surgery in neonates whose congenital heart defect depends on that duct for survival.
Risks. It carries a boxed warning, the strongest kind there is, because about one in ten treated newborns stop breathing, most often the smallest and usually in the first hour; it is given only where a ventilator is to hand. Extra bone on the outside of the long bones is on the label's list of side effects too.
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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.
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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.