Prostaglandins
COX-1, COX-2 and the four receptors for PGE2 in bone and cartilage, the prostaglandin mechanical loading releases, and what NSAIDs do to bone healing.
Cells of both the bone-forming and the bone-resorbing lineage produce PGE2 in quantity, COX-2 accounts for most of what bone makes, and it is degraded quickly once released.
In this article
- What loading releases
- COX-2 in repair and in the plate
- People carrying too much PGE2
- What NSAIDs have been measured to do
- Compounds
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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.