TissueGene-C
Withdrawn or never marketedMeasured in people, not heightBy injectionNucleic acidAlso Invossa
Cells injected into an arthritic knee, some of them engineered to release TGF-β1 so the joint keeps getting a supply of it.
An allogeneic cell therapy for knee osteoarthritis: ordinary human chondrocytes mixed with a second component engineered to secrete TGF-β1, injected into the joint so the cells act as a local pump of the protein.
Risks. It appeared safe. The problem was that it was not what it was said to be, which is why its approval was withdrawn, and its proposed mechanism has since shrunk to reducing inflammation.
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