Lonapegsomatropin

Hormones · In Growth hormone

3D structure of human growth hormone, the hormone it releases (PDB 1HGU)
Structure: human growth hormone, the hormone it releases. Image from the RCSB PDB (RCSB.org) of PDB ID 1HGU (Chantalat et al., 1995)

Approved for a growth disorderHeight measured in peopleBy injectionProtein or enzymeAlso Skytrofa

Growth hormone attached to a carrier that lets it go slowly, so the hormone that reaches the body is the ordinary one.

A long-acting formulation: a prodrug on a carrier, releasing unmodified somatropin. FDA approved August 2021.

Risks. No boxed warning, but its label carries fourteen warnings: among them rising pressure inside the skull, a hip growth plate that can slip out of place, worsening scoliosis, diabetes, a higher cancer risk in children who have had radiation to the head, and sudden death in children with Prader-Willi syndrome.

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  • Risks and side effects, members only

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What has been measured, in whom, with every source, and what it does to the rest of you. And every article in the library.

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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.