GrowTallest

Glucocorticoids

The best-documented growth suppressor there is, the randomised trial that put a number on what an inhaled steroid costs in adult height, and what is known about blocking it.

HormonesUpdated

4 min read16 sources

Glucocorticoids hold growth back three ways: directly on cartilage cells, by blunting growth hormone and IGF-1, and by turning down Indian hedgehog and CNP. The columns of dividing cells come out shorter. cartilage cellsGH and IGF-1IHH and CNPusualon steroidsGlucocorticoidThree brakesShorter columns

Cortisol and the synthetic corticosteroids, acting through the glucocorticoid receptor. The direction is settled: excess suppresses longitudinal growth, dose-dependently, measured in randomised trials with adult height as the endpoint.

In this article

  • Measured cost in adult height
  • Blocking cortisol
  • Summary

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Educational content, not medical advice. Nothing here is a recommendation to take or stop taking anything — talk to a doctor about your own situation.